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I am not in to natural/herbal supplements period. However, I am experiencing inflammation not only in my joints, but also in my brain possibly. I have just started taking turmeric. I just realized that it probably doesn't cross the blood/brain barrier so it was a useless purchase. I'm always sceptical of these products because I once had a doctor insist that I take glucosamine sulfate, so I took it for a couple of weeks and had explosive diahrrea for a further two weeks after I stopped taking it. After that experience I have not touched anything herbal.